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Recent Publications
DeVore, N.M., Smith, B.D., Wang, J.L., Lushington, G.H., and Scott, E.E. (2009)
Key residues controlling binding of diverse ligands to human cytochrome P450 2A Enzymes. Drug Metab. Dispos. 37:1319-1327.
Porubsky, P.R., Meneely, K.M., and Scott, E.E. (2008)
Structures of human cytochrome P450 2E1: Insights into the binding of inhibitors and both smallmolecular weight and fatty acid substrates. J. Biol. Chem.
DeVore, N.M., Smith, B.D., Urban, M.J., and Scott, E.E. (2008)
Key residues controlling phenacetin metabolism by human cytochrome P450 2A enzymes
. Drug Metab. Dispos. (in press).
Miller, M.A., Scott, E.E., and Limberg, J. (2008)
Expression, purification, crystallization and preliminary X-ray studies of a proly-4-hydroxylase protein from Bacillus anthracis
. Acta Crystallogr. F. 64:788-791.
Reed, T.M., Hirakawa, H., Mure, M., Scott, E.E., and Limberg, J. (2008)
Expression, purification and crystallization and preliminary X-ray studies of histamine dehydrogenase from Nocardiodes simplex.
Acta Crystallogr. F. 64:785-787.
Porubsky, P.R., Scott, E.E., and Williams, T.D. (2008)
p-Dimethylaminocinnamaldehyde derivatization for colorimetric detection and HPLC-UV/Vis-MS/MS identification of indoles.
Arch. Biochem. Biophys. 475:14-17.
Schlicht, K.E., Michno, N., Smith, B.D., Scott, E.E., and Murphy, S.E. (2007)
Functional characterization of CYP2A13 polymorphisms
. Xenobiotica. 37:1439-1349.
Smith B.D., Sanders J.L., Porubsky P.R., Lushington G.H., Stout C.D., and Scott, E.E. (2007)
Structure of the human lung cytochrome P450 2A13.
J. Biol. Chem. 282:17306-17313.
Scott E.E. and Halpert J.R. (2005)
Structures of cytochrome P450 3A4
. Trends in Biochem. Sci. 30:5-7.
Li W., Liu H., Scott E.E., Grater F., Halpert J.R., Luo X., Shen J., and Hiang H. (2005)
Possible pathway(s) of testosterone egress from the active site of cytochrome P450 2B1: A steered molecular dynamics simulation
. Drug Metab Dispos. 33:910-919.
Honma W., Li W., Liu H., Scott, E.E., and Halpert, J.R. (2005)
Functional role of residues in the helix B' region of cytochrome P450 2B1
. Arch. Biochem. Biophys. 435:157-165.