histone pairing
  Early germline development in the female germarium of D. melanogaster. Red staining (orb) indicates 16 nuclei cysts, one of which is the oocyte nucleus. Green indicates a FISH probe to the histone cluster, which like all loci in Drosophila, is paired in both germline and somatic cells.
Justin Blumenstiel
email: jblumens at ku.edu
University of Kansas
Lawrence, KS 66045
Office Phone: (785) - 864 - 3915
Lab Phone: (785) - 864 - 4119


What are the forces that drive the evolution of species and genomes? Unlike clonal organisms, sexually reproducing species reproduce by mixing the genetic material from different individuals. This sets the stage for genetic conflict. We are interested in how genetic conflct shapes patterns and processes of evolution at the molecular level. In particular, we are interested in how genetic conflict shapes:

-epigenetic silencing by piRNA and siRNA

-genome evolution and transposable elements

-the molecular evolution of the piRNA machinery

-the mechanisms of gametogenesis

-recombination rates and mutation rates

-transposable element dynamics

-hybrid incompatability

To study these topics, we work with different species of Drosophila, using a variety of approaches which include molecular biology, population genetics, cytogenetics, evolutionary modeling and modern methods of high-throughput sequencing.


Interested in becoming a member of the lab? We are now looking for students interested in evolutionary genetics and epigenetics to join our team. Please feel free to email me for more information:

jblumens at ku.edu




      Copyright © Justin Blumenstiel 2009