Blumenstiel Lab

BLUMENSTIEL LAB

genomics, genetics, epigenetics, and molecular evolution

Two different species of small silencing RNA are epigenetically transmited through the female germline. In the absence of maternally loaded Penelope endo-siRNA and piRNA, hybrids that inherit the Penelope element from their father have high levels of sterility.

Publications

1. Castillo, D.M., Mell, J.C., Box, K.S. and Blumenstiel, J.P. Molecular evolution under increasing transposable element burden in Drosophila: A speed limit on the evolutionary arms race. BMC Evolutionary Biology. 2011. Here.

2. Blumenstiel JP. Evolutionary dynamics of transposable elements in a small RNA world. Trends in Genetics. 27(1):23-31. 2011. Here.

3. Blumenstiel JP. Telomeres: A new means to an end. Current Biology. 21(1):R32-R3. 2011. Here.

4. JP Blumenstiel, AC Noll, JA Griffiths, AG Perera, KN Walton, WD Gilliland, RS Hawley and K. Staehling-Hampton. Identification of EMS-Induced mutations in Drosophila melanogaster by Whole-Genome Sequencing. Genetics. 182:25-32. 2009. Here.

5. JP Blumenstiel, R Fu, WD Theurkauf and RS Hawley. Components of the RNAi machinery that mediate long distance chromosome interactions are dispensable for meiotic and mitotic pairing. Genetics. 180:1355-1365. 2008. Here

6. JK Jeffress, SL Page, SK Royer, ED Belden, JP Blumenstiel, LK Anderson and RS Hawley. The formation of the central element of the synaptonemal complex may occur by multiple mechanisms: the roles of the N- and C-terminal domains of the Drosophila C(3)G protein in mediating synapsis and recombination. Genetics. 177(4):2445-56. 2007. Here.

7. JP Blumenstiel. Sperm competition can drive a male-biased mutation rate. J. Theor. Biol. 249(3):624-32. 2007. Here.

8. JP Blumenstiel and DL Hartl. Evidence for maternally transmitted small interfering RNA in the repression of transposition in Drosophila virilis. PNAS. 102(44):15965-70. 2005. Here.

9. DE Neafsey, JP Blumenstiel and DL Hartl. Different regulatory mechanisms underlie similar transposable element profiles ini pufferfish and fruitflies. Mol. Biol. Evol. 21(12):2310-8. 2004. Here.

10. JP Blumenstiel, DL Hartl and ER Lozovsky. Patterns of insertion and deletion in contrasting chromatin domains. Mol. Biol. Evol. 19(12):2211-25. 2002. Here.

11. B Jordan, A Charest, JF Dowd, JP Blumenstiel, RF Yeh, A Osman, DE Housman and JE Landers. Genome complexity reduction for SNP genotyping analysis. PNAS. 99(5):2942-7. 2002. Here.

12. H Kawasaki, GM Springett, S Toki, JJ Canales, P Harlan, JP Blumenstiel, EJ Chen, IA Bany, N Mochizuki, A Asbacher, M Matsuda, DE Housman and AM Graybiel. A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia. PNAS. 95(22):13278-83. 1998. Here.