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30. Rathinavelan T, Zhang L. Picking WL, Weis DD, De Guzman RN, Im W. A Repulsive Electrostatic Mechanism for Protein Export through the Type III Secretion Apparatus. Biophys. J. In press 2009. 29. Estrada DF, Boudreaux DM, Zhong D, St. Jeor SC, De Guzman RN. The Hantavirus Glycoprotein G1 Tail Contains a Dual CCHC-Type Classical Zinc Fingers. J. Biol. Chem. 284, 8654-60, 2009. 28. Wang Y, Boudreaux DM, Estrada DF, Egan CW, St. Jeor SC, De Guzman RN. NMR structure of the N-terminal coiled coil domain of the Andes hantavirus nucleocapsid protein. J. Biol. Chem. 283, 28297-304, 2008. 27. Wang Y, Zhang L, Picking WL, Picking WD, De Guzman RN. Structural dissection of the extracellular moieties of the type III secretion apparatus. Mol. BioSyst. 4, 1176-80, 2008. 26. Wang, Y, Ouellette, AN, Egan, CW, Rathinavelan, T, Im, W, and De Guzman, RN. Differences in the electrostatic surfaces of the type III secretion needle proteins PrgI, BsaL, and MxiH. J. Mol. Biol. 371, 1304-1314, 2007. 25. Zhang, L, Wang, Y, Olive, AJ, Smith, ND, Picking, WD, De Guzman, RN, and Picking, WL. Identification of the MxiH needle protein residues responsible for anchoring IpaD to the type III secretion needle tip. J. Biol. Chem. 282, 32144-32151, 2007. 24. Zhang, L, Wang, Yu, Picking, WL, Picking, WD, De Guzman, RN. Solution Structure of Monomeric BsaL, the Type III Secretion Needle Protein of Burkholderia pseudomallei. J. Mol. Biol. 359, 322-330, 2006. 23. De Guzman RN, Goto NK, Dyson HJ, Wright PE. Structural basis for cooperative transcription factor binding to the CBP coactivator. J Mol Biol. 355, 1005-1013, 2006. 22. De Guzman RN, Wojciak JM, Martinez-Yamout MA, Dyson HJ, Wright PE. CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding. Biochem 18, 490-497, 2005. 21. De Guzman RN, Martinez-Yamout MA, Dyson HJ, Wright PE. Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites. J Biol Chem. 279, 3042-3049, 2004. 20. Kamikubo Y, De Guzman R, Kroon G, Curriden S, Neels JG, Churchill MJ, Dawson P, Oldziej S, Jagielska A, Scheraga HA, Loskutoff DJ, Dyson HJ. Disulfide bonding arrangements in active forms of the somatomedin B domain of human vitronectin. Biochem 43, 6519-6534, 2004. 19. Zor T, De Guzman RN, Dyson HJ, Wright PE. Solution structure of the KIX domain of CBP bound to the transactivation domain of c-Myb. J Mol Biol. 337, 521-534, 2004. 18. Won HS, Low LY, De Guzman R, Martinez-Yamout MA, Jacob U, Dyson HJ. The Zinc-dependent Redox Switch Domain of the Chaperone Hsp33 has a Novel Fold. J Mol Biol. 341, 893, 2004. 17. Dames SA, Martinez-Yamout M, De Guzman RN, Dyson HJ, Wright PE. Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response. Proc. Natl. Acad. Sci. U.S.A. 99, 5271-5276, 2002. PMID: 11959977 16. De Guzman RN, Liu HY, Martinez-Yamout M, Dyson HJ, Wright PE. Solution Structure of the TAZ2 (CH3) Domain of the Transcriptional Adaptor Protein CBP. J. Mol. Biol. 303, 243-253, 2000. PMID: 11023789 15. Amarasinghe GK, De Guzman RN, Turner RB, Chancellor KJ, Wu ZR, Summers MF. NMR structure of the HIV-1 nucleocapsid protein bound to stem-loop SL2 of the psi-RNA packaging signal. Implications for genome recognition. J Mol Biol. 301, 491-511, 2000. PMID: 10926523 14. Amarasinghe GK, De Guzman RN, Turner RB, Summers MF. NMR structure of stem-loop SL2 of the HIV-1 psi RNA packaging signal reveals a novel A-U-A base-triple platform. J Mol Biol. 299, 145-156, 2000. PMID: 10860728 13. Klein DJ, Johnson PE, Zollars ES, De Guzman RN, Summers MF. The NMR structure of the nucleocapsid protein from the mouse mammary tumor virus reveals unusual folding of the C-terminal zinc knuckle. Biochemistry 39, 1604-1612, 2000. PMID: 10677209 12. De Guzman RN, Wu ZR, Stalling CC, Pappalardo L, Borer PN, Summers MF. Structure of the HIV-1 nucleocapsid protein bound to the SL3 psi-RNA recognition element. Science 279, 384-388, 1998. PMID: 9430589 11. Lee BM, De Guzman RN, Turner BG, Tjandra N, Summers MF. Dynamical behavior of the HIV-1 nucleocapsid protein. J Mol Biol. 279, 633-649, 1998. PMID: 9641983 10.McDonnell NB, De Guzman RN, Rice WG, Turpin JA, Summers MF. Zinc ejection as a new rationale for the use of cystamine and related disulfide-containing antiviral agents in the treatment of AIDS. J Med Chem. 40, 1969-1976, 1997. PMID: 9207937 9. Rice WG, Turpin JA, Huang M, Clanton D, Buckheit RW Jr, Covell DG, WallqvistA, McDonnell NB, De Guzman RN, Summers MF, Zalkow L, Bader JP, Haugwitz RD, Sausville EA. Azodicarbonamide inhibits HIV-1 replication by targeting the nucleocapsid protein. Nat Med. 3, 341-345, 1997. PMID: 9055865 8.De Guzman, RN, Yan-Fei Shen, Brenda R. Shaw, Steven L. Suib, and Chi-Lin O'Young. Role of Cyclic Voltammetry in Characterizing Solids: Natural and Synthetic Manganese Oxide Octahedral Molecular Sieves. Chemistry of Materials 5, 1395-1400, 1993. 7. Y. F. Shen, De Guzman, RN, R. P. Zerger, S. L. Suib, C. L. O'Young. Synthesis of Manganese Oxide Octahedral Molecular Sieves (OMS). Studies in Surface Science and Catalysis 83, 19-24, 1994. 6. Y. G. Yin, W. Q. Xu, De Guzman, RN, Y. F. Shen, S. L. Suib, and C. L. O'Young. Temperature Programmed Desorption and Reduction Studies of Octahedral Molecular Sieves. Studies in Surface Science and Catalysis 84, 453-460, 1994. 5. Y. G. Yin, W. Q. Xu, De Guzman, RN, S. L. Suib, and C. L. O'Young. Studies of Stability and Reactivity of Synthetic Cryptomelane-like Manganese Oxide Octahedral Molecular Sieves. Inorganic Chemistry 33, 4384-4389, 1994. 4. De Guzman, RN, Yan-Fei Shen, Edward J. Neth, Steven L. Suib, Chi-Lin O'Young, Steven Levine, and John M. Newsam. Synthesis and Characterization of Octahedral Molecular Sieves (OMS-2) Having the Hollandite Structure. Chemistry of Materials 6, 815-821, 1994. 3. De Guzman, RN, A. Awaluddin, Y. F. Shen, Z. R. Tian, S. L. Suib, S. Ching, and C. L. O'Young. Electrical Resistivity Measurements on Manganese Oxides with Layer and Tunnel Structures: Birnessites, Todorokites, and Cryptomelanes. Chemistry of Materials 7, 1286-1292, 1995. 2. Awaluddin, A. De Guzman, RN, Challa V. Kumar, Steven L. Suib, Sandra L. Burkett, and Mark E. Davis. Quenching of Tris(2,2'-bipyridine)ruthenium(II) Luminescence by Cobalt(III) Polypyridyl Complexes in Different Sites in and on Clays. Journal of Physical Chemistry 99, 9886-9892, 1995. 1. Shen YF, Zerger RP, De Guzman RN, Suib SL, McCurdy L, Potter DI, O'Young CL. Manganese Oxide Octahedral Molecular Sieves: Preparation, Characterization, and Applications. Science 260, 511-515, 1993. Reviews, Invited Book Chapters & Patents • De Guzman, RN. Bacterial Nanoinjectors. Chem. Biol. News & Res. 3, B87, 2008. • De Guzman, RN; Martinez-Yamout, M; Dyson, HJ; & P.E. Wright. Structure and Function of the CBP/p300 TAZ Domains, Chapter 17, Zinc Finger Proteins: From Atomic Contact to Cellular Function, Edited by Shiro Iuchi and Natalie Kuldell, Landes Bioscience, 2004. • De Guzman RN, Turner RB, Summers MF. Protein-RNA recognition. Biopolymers 48, 181-195, 1998. PMID: 10333745 • O’Young,CL; Shen, YF; De Guzman, RN; & Suib, SL. Metal-substituted octahedral manganese oxide molecular sieves and their manufacture. PCT Int. Appl. WO 95 25,693 (Cl. CO1B39/00), 28 Sep 1995, US Appl. 215,496, 21 Mar 1994.
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